Agave sensu lato appeared around 8 Mya. The best supported diversification model for Agavoidae shows two shifts around 8 Mya. Agave sensu lato speciation rate has been increasing towards the present. Nectarivorous bats from the Glossophaginae subfamily originated around 7 Mya. Agave and their pollinating bats share a diffuse coevolutionary history.